In a mostly vampiric world, a corporation run by vampires harvests the remaining humans while researching a synthetic blood substitute. But a band of humans, led by an ex-vampire, seeks freedom.
An Alaskan town experiences darkness for a month each year. After the last rays of light fade, a group of vicious vampires attacks the town. A couple stands between the vampires and the survivors.
Viago, Vladislav, Deacon, and Petyr are vampires who share a flat. Deacon's servant Jackie leaves her ex-boyfriend Nick inside. Petyr turns him into a vampire and he soon joins them as a flatmate.
Deacon Frost, a vampire, kills the elders of the underground vampiric society in order to gain control over his kind. To cement his powers, he needs the blood of Blade, a half-human vampire hunter.
Sang-hyeon is a priest. His life changes for the worse when he willingly participates in a medical experiment and gets affected by vampirism.
After the death of his wife and daughter, Spanish lord Louis is turned into a vampire by Lestat de Lioncourt. To keep Louis by his side, Lestat converts a plague-ridden girl.
When Elisabeta commits suicide, an enraged Vlad Dracula swears to avenge her death. Things take a turn when he meets Mina and takes her to be the reincarnation of Elisabeta.